Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/5341
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dc.contributor.authorOgbole, O. O.-
dc.contributor.authorEkor, M. N.-
dc.contributor.authorOluremi, B. B.-
dc.contributor.authorAjaiyeoba, E. O.-
dc.contributor.authorAyoola, M. A.-
dc.date.accessioned2021-04-14T12:34:08Z-
dc.date.available2021-04-14T12:34:08Z-
dc.date.issued2007-03-
dc.identifier.urihttp://hdl.handle.net/123456789/5341-
dc.description.abstractAbstract The methanolic extracts of Hippocratea indica root bark and Poga oleosa fruits were investigated for anti-inflammatory and antimicrobial activities. Both extracts inhibited carrageenan-induced paw oedema significantly in rats in a dose-dependent manner in 4 h. H. indica inhibited oedema significantly at the minimal dose (125 mg/ml, p< 0.05) from 2 h onward, and gave 100% inhibition in 4 h. at 250 mg/kg. It was shown to be a more potent anti-inflammatory agent than P. oleosa. Also, H. indica extract exhibited greater antimicrobial activity against tested bacteria, with Staphylococcus aureus being the most susceptible bacterium (MIC, 16 mg/ml). Both plants were inactive against Candida albicans. These results confirm the anti-inflammatory and antibacterial activities of the two plants.en_US
dc.language.isoenen_US
dc.subjectHippocratea indicaen_US
dc.subjectPoga oleosaen_US
dc.subjectanti-inflammatoryen_US
dc.subjectantimicrobialen_US
dc.titleANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF HIPPOCRATEA INDICA ROOT BARK AND POGA OLEOSA FRUITSen_US
dc.typeArticleen_US
Appears in Collections:School of Medical Sciences

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