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http://hdl.handle.net/123456789/9116
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DC Field | Value | Language |
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dc.contributor.author | Bhatt, Shantanu | - |
dc.contributor.author | Anyanful, Akwasi | - |
dc.contributor.author | Kalman, Daniel | - |
dc.date.accessioned | 2023-10-05T18:38:45Z | - |
dc.date.available | 2023-10-05T18:38:45Z | - |
dc.date.issued | 2011-09 | - |
dc.identifier.uri | http://hdl.handle.net/123456789/9116 | - |
dc.description.abstract | Enteropathogenic Escherichia coli (EPEC) requires the tnaA-encoded enzyme tryptophanase and its sub- strate tryptophan to synthesize diffusible exotoxins that kill the nematode Caenorhabditis elegans. Here, we demonstrate that the RNA-binding protein CsrA and the tryptophan permease TnaB coregulate tryptophanase activity, through mutually exclusive pathways, to stimulate toxin-mediated paralysis and killing of C. elegans. | en_US |
dc.language.iso | en | en_US |
dc.publisher | JOURNAL OF BACTERIOLOGY, | en_US |
dc.title | CsrA and TnaB Coregulate Tryptophanase Activity To Promote Exotoxin-Induced Killing of Caenorhabditis elegans by Enteropathogenic Escherichia coli | en_US |
dc.type | Article | en_US |
Appears in Collections: | School of Allied Health Sciences |
Files in This Item:
File | Description | Size | Format | |
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CsrA and TnaB Coregulate Tryptophanase Activity To Promote.pdf | Main article | 537.67 kB | Adobe PDF | View/Open |
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