Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/9583
Title: Bispecific Antibodies (bsAbs): Promising Immunotherapeutic Agents for Cancer Therapy
Authors: Acheampong, Desmond O.
Adokoh, Christian K.
Ampomah, Paulina
Agyirifo, Daniel S.
Dadzie, Isaac
Ackah, Francis A.
Asiamah, Ernest A.
Keywords: Antibody,
bispecific antibody (BsAb),
immunotherapeutic agent,
cancer therapy,
diabody,
antitumor.
Issue Date: 2017
Publisher: Protein & Peptide Letters
Abstract: Abstract: Antibodies have become the preferred therapeutic treatment option for cancers. Antibody therapy is associated with low toxic profile and specific in its activity, unlike chemotherapy and ra- diotherapy. Types of tumor are known to express multiple receptors that cross-talk to activate per- petual growth, proliferation and metastasis, and inhibit apoptosis in such tumors. Bispecific antibod- ies (BsAbs) are therefore the preferred agent for the treatment of such cancers due to its unique char- acteristics. This review discusses up to date therapeutic potentials of BsAbs.
URI: http://hdl.handle.net/123456789/9583
Appears in Collections:School of Allied Health Sciences

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