Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/9932
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBrenyah, Ruth C.-
dc.contributor.authorGborbidzi, Mildred E.-
dc.contributor.authorNkansah, Charles-
dc.contributor.authorOsei-Boakye, Felix-
dc.date.accessioned2023-10-23T18:12:29Z-
dc.date.available2023-10-23T18:12:29Z-
dc.date.issued2017-
dc.identifier.urihttp://hdl.handle.net/123456789/9932-
dc.description.abstractObjective: This study investigated chronic kidney disease (CKD) and urine abnormalities in highly active antiretroviral therapy naïve (HAART-naïve) human immunodeficiency virus (HIV) infected adults, presenting to two antiretroviral therapy (ART) clinics in the Volta region of Ghana. Methods: A cross-sectional study of 100 newly diagnosed HIV/AIDS patients attending ART clinics of the St. Anthony’s and Ho Municipal hospitals both in the Volta region was conducted. Vital clinical history and socio-demographic data were recorded from the folder of eligible participants. Blood and urine samples were collected for serum creatinine estimation; urinalysis was performed with dipstick and light microscopy. CKD was assessed with the Kidney Disease Improving Global Outcome (KDIGO) guidelines. Results: Nine percent (9%) of the participants had CKD (eGFR<60 mL/min/1.73 m²). Prevalence of CKD was higher (88.9%) in females than in males (11.1%). Median creatinine levels were significantly higher in males than in females (P=0.0103). Eighteen percent (18%), 13%, 11% of the participants had proteinuria, pyuria and haematuria respectively. On urine microscopy, we recorded 8% (8/100) crystalluria (7/8 -calcium oxalate and 1/8 -triple phosphate), 9% epithelial cells, 20% pus cells and 7% red blood cells among our participants. Participants with confirmed CKD had more pyuria and haematuria than those without CKD. Conclusion: This study revealed a 9% prevalence of CKD among our participants with the condition being more common in females. Urine abnormalities like proteinuria, haematuria, pyuria and crystalluria were common in our participants. Routine urinalysis and screening for CKD in HIV/AIDS patients should be strengthened as it will help in early detection of renal abnormalities.en_US
dc.language.isoenen_US
dc.publisherBritish Journal of Medicine & Medical Researchen_US
dc.subjectChronic kidney disease;en_US
dc.subjecturine abnormalities;en_US
dc.subjecthighly active antiretroviral therapy naïve;en_US
dc.subjectestimated GFR;en_US
dc.subjectHIV/AIDS.en_US
dc.titleUrine Abnormalities and Chronic Kidney Disease in Highly Active Antiretroviral Therapy-naive Adults: A Cross-sectional Studyen_US
dc.typeArticleen_US
Appears in Collections:School of Allied Health Sciences

Files in This Item:
File Description SizeFormat 
Urine Abnormalities and Chronic Kidney Disease in.pdfMain article178.18 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.