Gentamicin (GM) is one of the most important of the aminoglycoside antibiotics used widely for the treatment of serious and life-threatening infections and whose clinical use is limited by its nephrotoxicity. As the ...

This study investigated the effect of selective inhibition of phosphodiesterase-5 on hepatotoxicity and genotoxicity induced by adriamycin in rats. Thirty male Wistar rats (150 – 250 g) were randomly assigned into six ...

Recent studies have indicated an increased incidence of toxic neuropathies among waste management workers (WMW) possibly linked to increased detection of heavy metals in municipal solid wastes. The present study evaluated ...

Abstract This study set out to answer six research questions as to whether University of Cape Coast School of Medical Sciences (UCCSMS) students were truly sleep deprived and whether there was a significant difference in ...

analgesics have fueled the drive for the search for more analgesics with better side effect profiles. Geraniin, the most dominant secondary metabolite in the aqueous extract of the aerial parts of Phyllanthus muellerianus, ...

The popular fruit tree of Annona muricata L. (Annonaceae), known as soursop and graviola, is a widely distributed plant in Central and South America and tropical countries. Leaves of A. muricata have been reported to possess ...

Sustained release diclofenac sodium matrix tablets (~100 mg) were prepared by wet granulation using blends of cashew gum, xanthan gum and HPMC as drug release modifiers. The flow properties of diclofenac sodium granules ...

The roots of Jatropha curcas are used traditionally to treat pain. The present study evaluated the analgesic property of ethanolic extract of Jatropha curcas (JAT) in acute and chronic muscle pain models. Acute muscle ...

Background: Advertisements of most alcoholic beverages in Ghana persuasively entice consumers with herbal constituents believed to enhance sexual performance, although, alcohol has negative effect onfertility. The impact ...

Context: Fruits of Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) are used traditionally to manage arthritis, headache and other pain disorders. Objective: The analgesic properties of the X. aethiopica ethanol fruit ...