School of Medical Sciences: Recent submissions

Now showing items 221-240 of 418

Oncogenic human papillomavirus infection and genotypes characterization among sexually active women in Tenkodogo at Burkina Faso, West Africa

Ouedraogo, Rogomenoma Alice; Zohoncon, Théodora Mahoukèdè; Guigma, Sindimalgdé Patricia; Traore, Ina Marie Angèle; Ouattara, Abdoul Karim; Ouedraogo, Marie; Djigma, Florencia Wendkuuni; Obiri-Yeboah, Dorcas; Ouedraogo, Charlemagne; Simpore, Jacques (Papillomavirus Research, 2018)

Objective: This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus (HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso. Methods: Among 131 sexually ...
Natural Killer Cells and Innate Immunity in HIV-2 Infection

Nuvor, Samuel Victor (Springer Reference, 2014)

In contrast to the extensive efforts made to learn more about HIV-1 in the fields of epidemiology, geographical distribution, and viral pathogenesis, very little work has been carried out to understand the interactions ...
Natural Killer Cell Function Is Well Preserved in Asymptomatic Human Immunodeficiency Virus Type 2 (HIV-2) Infection but Similar to That of HIV-1 Infection When CD4 T-Cell Counts Fall

Nuvor, Samuel Victor; Sande, Marianne van der; Rowland-Jones, Sarah; Whittle, Hilton; Jaye, Assan (JOURNAL OF VIROLOGY, 2006)

Natural killer (NK) cells are potent effectors of natural immunity and their activity prevents human immunodeficiency virus type 1 (HIV-1) viral entry and viral replication. We sought to determine whether NK immune responses ...
Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of Ghana

Amoah, L. E.; Nuvor, S. V.; Obboh, E. K.; Acquah, F. K.; Asare, K.; Singh, S. K.; Boampong, J. N.; Theisen, M.; Williamson, K. C. (Parasites & Vectors, 2017)

Background: Plasmodium falciparum genetic diversity and multiplicity of infection (MOI) are parasite features that have been suggested to influence the acquisition of protective immunity against malaria. This study sought ...
Molecular Genotyping of Human Papillomavirus among HIV-infected and HIV- uninfected Women in Ouagadougou, Burkina Faso

DJIGMA, Florencia Wendkuuni; ZOHONCON, Théodora Mahoukèdè; DOUAMBA, Zoénabo; SORGHO, Pegdwendé Abel; Obiri-Yeboah, Dorcas; OUATTARA, Abdoul Karim; SAGNA, Tani; TRAORE, Lassina; GHILAT-AVOID-BELEM, Nadine W.; SANOGO, Korotomi; SEMPORE, Jedida; YONLI, Albert Théophane; PIETRA, Virginio; BISSEYE, Cyrille; OUEDRAOGO, Charlemagne; SIMPORE, Jacques (Journal of Medical Biomedical and Applied Sciences, 2020)

This study particularly focused on the human papillomavirus (HPV) that causes cervical cancer. The objective was to study the profile and genotypic prevalence of HPV among HIV infected and HIV uninfected women. Method: ...
Molecular Characterization of High-Risk Human Papillomavirus in Women in Bobo-Dioulasso, Burkina Faso

Traore, Ina Marie Angèle; Zohoncon, Théodora Mahoukèdè; Dembele, Adama; Djigma, Florencia W.; Obiri-Yeboah, Dorcas; Traore, Germain; Bambara, Moussa; Ouedraogo, Charlemagne; Traore, Yves; Simpore, Jacques (BioMed Research International, 2016)

High-risk human papillomavirus (HPV) is found in over 99% of cervical cancers. The aim of this study was to determine the prevalence of HPV in a population of women in Bobo-Dioulasso and to identify the high-risk types ...
Modulation of cyptosporidiosis by CD4 levels in chronic diarrhoea HIV/AIDS individuals visiting Tarkwa Municipal hospital, Ghana

Kwakye-Nuako, Godwin; Boampong, Johnson Nyarko; Dong, Mark Kweku; Obiri-Yeboah, Dorcas; Opoku, Yeboah Kwaku; AmoakoSakyi, Daniel; Asare, Kwame Kumi (Asian Pacific Journal of Tropical Disease, 2016)

Objective: To investigate the role CD4+ levels play in controlling diarrhea conditions caused by intestinal coccidian infections among HIV/AIDS infected individuals visiting Tarkwa Municipal Hospital. Methods: Fifty ...
Managing uncertainty in medicine quality in Ghana: The cognitive and affective basis of trust in a high-risk, low-regulation context

Hamill, Heather; Hampshire, Kate; Mariwah, Simon; Amoako-Sakyi, Daniel; Kyei, Abigail; Castelli, Michele (Social Science & Medicine, 2019)

Where regulation is weak, medicine transactions can be characterised by uncertainty over the drug quality and efficacy, with buyers shouldering the greater burden of risk in exchanges that are typically asymmetric. Drawing ...
Major Polymorphisms of Genes Involved in Homocysteine Metabolism in Malaria Patients in Ouagadougou, Burkina Faso

Yameogo, Noé; Bazie, Bapio Valérie Elvira Jean Télesphore; Ouattara, Abdoul Karim; Yameogo, Pouiré; Compaore, Tegwinde Rebeca; Obiri-Yeboah, Dorcas; Djigma, Florencia Wenkuuni; Karou, Simplice Damintoti; Simpore, Jacques (Malaria Research and Treatment, 2017)

This study analyzed the four main polymorphisms of the genes in homocysteine metabolism in malaria patients. Forty-two randomly selected subjects, diagnosed positive for Plasmodium falciparum, were included. The four ...
Lipid and Lipoprotein Levels in Type 2 Diabetes Patients Attending the Central Regional Hospital in the Cape Coast Metropolis of Ghana

Acquah, Samuel; Boampong, Johnson N; Adusu, Justice; Achampong, Emmanuel K; Setorglo, Jacob; Obiri-Yeboah, Dorcas (International Journal of Health Research, 2011)

Purpose: To ascertain the prevalence of dyslipidaemia in diabetics in Cape Coast. Methods: This preliminary outpatient-based cross-sectional study was conducted in 79 diabetic patients (22 males and 57 females) receiving ...
Levels of serum eosinophil cationic protein are associated with hookworm infection and intensity in endemic communities in Ghana

Amoan, Benjamin; Adu, Bright; Frempong, Margaret T.; Sarkodie-Addo, Tracy; Nuvor, Samuel Victor; Wilson, Michael D.; Gyan, Ben (PLOS ONE, 2019)

Background The eosinophil cationic protein (ECP) is a cytotoxic protein mainly secreted by eosinophils granulocytes and plays a role in host defense against parasitic infections. Infection with Necator americanus (hookworm) ...
Knowledge and practice of exclusive breastfeeding among mothers in the tamale metropolis of Ghana

Nukpezah, Ruth Nimota; Nuvor, Samuel Victor; Ninnoni, Jerry (Reproductive Health, 2018)

Background: The prevalence of exclusive breastfeeding (EBF) for the first six months of life has remained low worldwide and in Ghana, despite strong evidence in support of its practice. This study was aimed at assessing ...
Knowledge and experience of a cohort of HIV-positive and HIV-negative Ghanaian women after undergoing human papillomavirus and cervical cancer screening

Stuart, Arabella; Obiri-Yeboah, Dorcas; Adu-Sarkodie, Yaw; Hayfron-Benjamin, Anna; Akorsu, Angela D.; Mayaud, Philippe (BMC Women's Health, 2019)

Background: Cervical cancer is the most common cancer in women in Ghana, but knowledge and experience of women who have had cervical screening is under-evaluated. This study examined knowledge and understanding of HPV and ...
Knowledge and attitude of patients with diabetes in government hospitals in the Upper West Region of Ghana

Kpekura, Stephen; Ninnoni, Jerry P. K.; Nuvor, Samuel V. (International Journal of Community Medicine and Public Health, 2018)

Background: Diabetes mellitus is a chronic progressive metabolic disorder characterized by hyperglycaemia mainly due to absolute or relative deficiency of insulin hormone. This study assessed the knowledge and attitude of ...
Intestinal Parasitosis among Primary School Pupils in Coastal Areas of the Cape Coast Metropolis, Ghana

Dankwa, Kwabena; Kumi, Ransford Oduro; Ephraim, Richard K. D.; Adams, Latif; Amoako-Sakyi, Daniel; Essien-Baidoo, Samuel; Nuvor, Samuel Victor (International Journal of TROPICAL DISEASE & Health, 2015)

Background: Intestinal parasitosis remains a major public health burden in developing countries such as Ghana. The burden of disease is heaviest among vulnerable populations and yet epidemiologic data from these populations ...
Intestinal Parasitic Infections Among Primary School Pupils in Elmina, A Fishing Community in Ghana

Dankwa, Kwabena; Addy-Lamptey, Priscilla; Latif, Adams; Essien-Baidoo, Samuel; Ephraim, Richard K.D (International Journal of Medical and Health Sciences, 2017)

Background: Intestinal parasitic infections are common in the developing world, particularly among communities with low socioeconomic status. Many of these infections are very often neglected making them a major public ...
Incidence of adverse events after discharge from a secondary hospital in northern Ghana

Iddrisu, Inusah D.; Anyanful, Akwasi; Nuvor, Samuel V. (International Journal of Community Medicine and Public Health, 2019)

Background: Adverse events involve unintended injuries or complications resulting in death, disability, harm or prolonged hospital stay that arise from health care management. This paper aims at giving insight into the ...
In vivo efficacy of top five surveyed Ghanaian herbal anti-malarial products

Wilmot, Dennis; Ameyaw, Elvis Ofori; Amoako‑Sakyi, Daniel; Boampong, Johnson Nyarko; Quashie, Neils Ben (Malaria Journal, 2017)

Background: Anti malarial herbal preparations (HPs) continue to enjoy high patronage in Ghana despite reports that the artemisinin based combination therapy (ACT), the recommended first choice for treatment of uncomplicated ...
In vivo Antimalarial Activity Evaluation of Two Cryptolepis sanguinolenta Based Herbal Decoctions

Tay, Sammy C K; Dankwa, Kwabena; Gbedema, Stephen Y; Sittie, Archibald A (Inventi Impact, 2011)

The antimalarial activity of two Cryptolepis sanguinolenta based herbal decoctions namely Cryptoquine and Nibima, were studied using Plasmodium berghei (ANKA) in mice. The herbal preparations were evaluated for chemosuppressive ...
Impact of glutathione S-transferase genes polymorphisms on human papillomavirus infection and precancerous lesions in West African women

OUEDRAOGO, Teega-Wendé Clarisse; DJIGMA, Florencia Wendkuuni; IDANI, Boureima; ZOHONCON, Théodora Mahoukèdè; SORGHO, Pegdwendé Abel; BADO, Prosper; TRAORE, Mah Alima Esther; OUATTARA, Abdoul Karim; SETOR, Marius Ayaovi; BELLO, Shoukrat Ohuwa Toyin; KAROU, Simplice Damintoti; HORO, Apollinaire; KOUAKOU, Kouame Privat; GOMINA, Moutawakilou; NAYAMA, Mady; CAPO-CHICHI, D. Callinice; SANNI, Ambaliou; OBIRI-YEBOAH, Dorcas; AKPONA, Simon; YONLI, Albert Théophane; OUEDRAOGO, Charlemagne; SIMPORE, Jacques (International Journal of Genetics and Molecular, 2020)

Genetic polymorphisms of certain classes of glutathione S-transferase (GST), enzyme responsible for the biotransformation of drugs and xenobiotics, have been associated with risk of several cancers such as cervical cancer. ...

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